PGT-M
Preimplantation genetic testing for monogenic disorders (PGT-M) is a genetic screening technique used during in vitro fertilization (IVF) to identify embryos with specific inherited genetic conditions. It is particularly used for couples at risk of passing on monogenic disorders, such as cystic fibrosis, sickle cell anemia, or Huntington’s disease. PGT-M involves extracting cells from embryos and analyzing them for known mutations associated with these conditions. The goal is to select embryos free of the genetic disorder for implantation. This procedure reduces the risk of passing on genetic diseases to the child. PGT-M is typically performed after embryo biopsy and genetic analysis. While it can provide valuable information, it requires prior knowledge of the genetic mutation in the family.
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